CETP
Metabolic Enzyme/Protease
11β-HSD(15)
15-PGDH(1)
ACC(10)
ACE(15)
AChE(47)
Adenylate Cyclase(12)
ALDH(14)
Aldose Reductase(5)
Aminopeptidase(19)
BACE(19)
Casein Kinase(51)
CAT(5)
Cathepsin(9)
CETP(13)
COMT(2)
CPG2(1)
CYPs(6)
Decarboxylase(3)
Dehydrogenase(131)
DGAT(4)
Dopamine beta-hydroxylase(2)
DPP(32)
Elastase(6)
FAAH(28)
Factor Xa(31)
Fatty Acid Synthase(17)
Ftase(2)
FXR(26)
Glucokinase(1)
GSNOR(2)
Guanylate Cyclase(13)
HMGCR(17)
IDH(7)
IDO(20)
IMPDH(2)
LDH(2)
LDL(8)
Lipase(17)
Lipid(12)
MAGL(6)
MAO(72)
MMP(78)
NAMPT(12)
Neprilysin(7)
Other Targets(10)
P450(112)
PAI-1(9)
Phosphatase(95)
Phospholipase(65)
PPAR(115)
Protein Phosphatase/PTP(6)
Renin(8)
Retinoid Receptor(37)
SCD(6)
Steroid Sulfatase (STS)(2)
Thioredoxin(1)
TPH(5)
Transferase(37)
Vitamin(44)
Xanthine Oxidase (XAO)(11)
CETP
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Granotapide
产品货号 : M34613
cas no: 594842-13-4
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, and hypertension. -
BMS-212122
产品货号 : M34524
cas no: 194213-64-4
BMS-212122 (UNII-0Z473OO6GB) is a potent inhibitor of microsomal triglyceride transfer protein (MTP) and has shown hypolipidemic effects in animal studies.BMS-212122 significantly reduced lipid content and monocyte-derived (CD68+) cells in atherosclerotic plaques. -
Dirlotapide
产品货号 : M33324
cas no: 481658-94-0
Dirlotapide (CP742033) 是一种选择性的微粒体甘油三酯转运蛋白 (MTP) 抑制剂,可以减轻糖尿病狗的体重。 -
Ro 5-3335
产品货号 : M17470
cas no: 30195-30-3
Ro 5-3335是核心结合因子(CBF)抑制剂;使用 CBF 融合蛋白优先杀死人类白血病细胞系 (IC50 = 1.1 μM)。 -
SR17018
产品货号 : M17433
cas no: 2134602-45-0
SR17018 是一种 mu-阿片受体 (MOR) 激动剂,与 GTPγS 结合,EC50 为 97 nM。