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S-Trityl-L-cysteine
CAS No. 2799-07-7
S-Trityl-L-cysteine ( NSC 83265 )
产品货号. M13853 CAS No. 2799-07-7
S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥316 | 有现货 |
|
| 100MG | ￥446 | 有现货 |
|
| 200MG | ￥648 | 有现货 |
|
| 500MG | ￥1077 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称S-Trityl-L-cysteine
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM).
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产品描述S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM); induces mitotic arrest in HeLa cells with an IC50 of 700 nM, and displays antitumor activity.
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同义词NSC 83265
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通路Cytoskeleton/Cell Adhesion Molecules
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靶点Kinesin
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受体Kinesin
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研究领域——
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适应症——
化学信息
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CAS Number2799-07-7
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分子量363.47
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分子式C22H21NO2S
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纯度>98% (HPLC)
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溶解度——
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SMILESC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)SCC(C(=O)O)N
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化学全称S-(Triphenylmethyl)-L-cysteine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Brier S, et al. Biochemistry. 2004 Oct 19;43(41):13072-82.
2. DeBonis S, et al. Mol Cancer Ther. 2004 Sep;3(9):1079-90.
3. Zhao J, et al. Am J Cancer Res. 2014 Jan 15;4(1):42-52.
2. DeBonis S, et al. Mol Cancer Ther. 2004 Sep;3(9):1079-90.
3. Zhao J, et al. Am J Cancer Res. 2014 Jan 15;4(1):42-52.
产品手册
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