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PF-2771
CAS No. ——
PF-2771 ( PF2771;PF 2771 )
产品货号. M17078 CAS No. ——
PF-2771 is a potent, selective CENP-E inhibitor with IC50 of 16.1 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PF-2771
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PF-2771 is a potent, selective CENP-E inhibitor with IC50 of 16.1 nM.
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产品描述PF-2771 is a potent, selective CENP-E inhibitor with IC50 of 16.1 nM; does not inhibit the ATPase activities of highly related kinesins (Eg5/KSP, chromokinesin and MCAK, IC50> 1 uM); selectively inhibits proliferation of basal breast cancer cell lines; regresses tumor growth correlated with increased phospho-HH3-Ser10 levels in a breast cancer xenograft tumor model.
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同义词PF2771;PF 2771
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通路Cytoskeleton/Cell Adhesion Molecules
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靶点Kinesin
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受体Kinesin
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量554.08
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分子式C29H36ClN5O4
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 32 mg/mL
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SMILES——
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化学全称(S)-N-(1-(4-(2-acetyl-1-methyl-1H-imidazol-4-yl)phenyl)-3-(2-(dimethylamino)acetamido)propan-2-yl)-3-chloro-4-isopropoxybenzamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Kung PP, et al. Mol Cancer Ther. 2014 Aug;13(8):2104-15.
产品手册
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