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ML-148
CAS No. 451496-96-1
ML-148 ( —— )
产品货号. M28159 CAS No. 451496-96-1
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1531 | 有现货 |
|
| 10MG | ￥2406 | 有现货 |
|
| 25MG | ￥4350 | 有现货 |
|
| 50MG | ￥6278 | 有现货 |
|
| 100MG | ￥8748 | 有现货 |
|
| 500MG | ￥17577 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ML-148
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).
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产品描述ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways.(In Vitro):ML148 (10 nM) reduces the apparent Km by half and decreases Vmax by 25%. ML148 shows selectivity with IC50s of 36000, >57500, >57500 nM for ALDH1A1, HADH2, HSD17β4, respectively.
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同义词——
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体GPR52
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研究领域——
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适应症——
化学信息
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CAS Number451496-96-1
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分子量319.4
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分子式C20H21N3O
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(C=1C=CC2=C(N=CN2C3=CC=CC(=C3)C)C1)N4CCCCC4
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Wang, C., Zhang, Y.-F., Guo, S., et al.GPR52 antagonist reduces huntingtin levels and ameliorates Huntington’s disease-related phenotypesJ. Med. Chem.64(2)941-957(2021)
产品手册
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