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HPV
The human papilloma viruses (HPVs) are DNA double strand viruses and of small size (approximately 8000 pairs of bases) that have cohabited with the human specie over dozens of millennia suffering relatively few changes in their genetic composition. These nearly 100 different types of papillomavirus identified express a characteristic tropism. The best known clinical expression of the viral infection is condylomas or genital warts, associated in approximately 90% of the cases by infections by HPVs 6 and 11 and, more rarely, with HPVs 42 and 16. Infection by HPV is basically a sexually transmitted disease. As such, both men and women are involved in the epidemiological chain of infection and are able at the same time to be asymptomatic carriers, transmitters and also victims of the infection by HPV.
References
1.Castellsagué X. Gynecol Oncol. 2008 Sep;110(3 Suppl 2):S4-7.
References
1.Castellsagué X. Gynecol Oncol. 2008 Sep;110(3 Suppl 2):S4-7.
Microbiology/Virology
HPV
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Human Papillomavirus (HPV) E7 protein 49-57
产品货号 : M30294
cas no: 151812-18-9
Human Papillomavirus (HPV) E7 protein (49-57) is the H-2d-restricted human papillomavirus (HPV) E749-57 epitope.
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HPV16 E7 (86-93)
产品货号 : M30253
cas no: 160212-93-1
This is amino acids 86 to 93 fragment of the human papilloma virus (HPV) type 16 oncoprotein E7. This HPV16-encoded peptide has very high affinity of binding to the HLA-A*0201 molecule.This immunogenic fragment may be used in vaccines for the prevention and treatment of cervical carcinoma.
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HPV16-E711-20 epitope
产品货号 : M30214
cas no: 160040-04-0
HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro.
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BILH-434
产品货号 : M15887
cas no: 760169-28-6
BILH-434 是一种有效的 HPV11 E1/E2/DNA 复合物抑制剂，可与 E2 蛋白的反式激活结构域 (TAD) 结合，Kd 为 40 nM。
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Teslexivir
产品货号 : M10309
cas no: 1075798-37-6
一种一流的小分子蛋白-蛋白抑制剂，可抑制 6 型和 11 型 HPV 的 E1 和 E2 蛋白之间的相互作用。
