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hDHODH-IN-5

CAS No. 2029049-77-0

hDHODH-IN-5 ( DHODH-IN-7 )

产品货号. M26160 CAS No. 2029049-77-0

hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1369 有现货
10MG ¥1993 有现货
25MG ¥3208 有现货
50MG ¥4771 有现货
100MG ¥6796 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    hDHODH-IN-5
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase.
  • 产品描述
    hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).(In Vitro):hDHODH-IN-5 induces differentiation in ER-HOX-GFP, THP1, and U937 human AML cell lines with EC50s of 3.6, 2.7, and 2.5 μM, respectively.
  • 同义词
    DHODH-IN-7
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Dehydrogenase
  • 受体
    p300
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2029049-77-0
  • 分子量
    390.4
  • 分子式
    C21H21F3N2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    FC(F)(F)c1ccc(cc1)C(=O)NCCC(=O)N[C@@H]1CCCc2ccccc12
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Mantelingu K, et al. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy. J Phys Chem B. 2007;111(17):4527-4534.
产品手册
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