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TMP-269
CAS No. 1314890-29-3
TMP-269 ( TMP 269;TMP269 )
产品货号. M11270 CAS No. 1314890-29-3
A potent and selective class IIa HDAC inhibitor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥535 | 有现货 |
|
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1328 | 有现货 |
|
| 25MG | ￥2219 | 有现货 |
|
| 50MG | ￥4001 | 有现货 |
|
| 100MG | ￥4836 | 有现货 |
|
| 200MG | ￥6958 | 有现货 |
|
| 500MG | ￥10449 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TMP-269
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent and selective class IIa HDAC inhibitor.
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产品描述A potent and selective class IIa HDAC inhibitor with IC50s of 126/80/36/19 nM for HDAC4/5/7/9; less potent or no inhibition for others HDAC isoforms (>2 uM); prevents cell cycle progression, DNA synthesis, and proliferation induced in response to G protein-coupled receptor/PKD1 activation in IEC-18 cells.
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同义词TMP 269;TMP269
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC4;HDAC5;HDAC7;HDAC9
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研究领域Cancer
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适应症——
化学信息
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CAS Number1314890-29-3
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分子量514.52
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分子式C25H21F3N4O3S
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 41 mg/mL
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SMILESO=C(NCC1(C2=NC(C3=CC=CC=C3)=CS2)CCOCC1)C4=CC=CC(C5=NOC(C(F)(F)F)=N5)=C4
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化学全称Benzamide, N-[[tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Lobera M, et al. Nat Chem Biol. 2013 May;9(5):319-25.
2. Sinnett-Smith J, et al. Am J Physiol Cell Physiol. 2014 May 15;306(10):C961-71.
3. Kikuchi S, et al. Leukemia. 2015 Sep;29(9):1918-27.
2. Sinnett-Smith J, et al. Am J Physiol Cell Physiol. 2014 May 15;306(10):C961-71.
3. Kikuchi S, et al. Leukemia. 2015 Sep;29(9):1918-27.
