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HPOB
CAS No. 1429651-50-2
HPOB ( —— )
产品货号. M11815 CAS No. 1429651-50-2
A potent and selective HDAC6 inhibitor (IC50=56 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥405 | 有现货 |
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| 10MG | ￥583 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称HPOB
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent and selective HDAC6 inhibitor (IC50=56 nM).
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产品描述A potent and selective HDAC6 inhibitor (IC50=56 nM); shows IC50>1.7 uM for the other HDACs, more potent than tubacin; selectively inhibits HDAC6 catalytic activity in vivo and in vitro; causes growth inhibition of normal and transformed cells but does not induce cell death; enhances the effectiveness of DNA-damaging anticancer drugs in transformed cells but not normal cells.
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同义词——
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC1;HDAC10;HDAC3;HDAC6;HDAC8
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研究领域Cancer
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适应症——
化学信息
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CAS Number1429651-50-2
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分子量314.34
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分子式C17H18N2O4
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESC1=CC=C(C=C1)N(CCO)C(=O)CC2=CC=C(C=C2)C(=O)NO
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化学全称Benzeneacetamide, 4-[(hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Lee JH, et al. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15704-9.
2. Li ZY, et al. Neurochem Int. 2016 Oct;99:239-51.
2. Li ZY, et al. Neurochem Int. 2016 Oct;99:239-51.
产品手册
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