• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Remodelin

CAS No. 949912-58-7

Remodelin ( —— )

产品货号. M16792 CAS No. 949912-58-7

A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥405 有现货
10MG ¥567 有现货
25MG ¥1069 有现货
50MG ¥1580 有现货
100MG ¥2333 有现货
200MG ¥3507 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Remodelin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
  • 产品描述
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules; significantly reduces the prevalence of misshapen nuclei in HGPS cells, prevents FTI-induced nuclear shape defects in normal fibroblasts and U2OS cells; does not affect Golgi apparatus integrity or tubulin polymer assembly, and does not cause cells to accumulate in mitosis.
  • 同义词
    ——
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    NAT10inhibitor
  • 研究领域
    Other Indications
  • 适应症
    ——

化学信息

  • CAS Number
    949912-58-7
  • 分子量
    282.36
  • 分子式
    C15H14N4S
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1
  • 化学全称
    Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Larrieu D, et al. Science. 2014 May 2;344(6183):527-32.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
产品手册
关联产品
  • HPOB

    A potent and selective HDAC6 inhibitor (IC50=56 nM).

  • CHDI-390576

    CHDI-390576 (CHDI390576) is a potent, cell permeable and CNS penetrant class IIa HDAC inhibitor.

  • AES-350

    AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively).