QCA276
CAS No. 2126819-40-5
QCA276 ( QCA 276;QCA-276 )
产品货号. M13384 CAS No. 2126819-40-5
QCA276 is a novel potent BET proteins inhibitor with IC50/Ki of 10/.3 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称QCA276
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述QCA276 is a novel potent BET proteins inhibitor with IC50/Ki of 10/.3 nM.
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产品描述QCA276 is a novel potent BET proteins inhibitor with IC50/Ki of 10/.3 nM, QCA276 is the BET ligand for PROTAC QCA570; effectively inhibits human BRD2, BRD3, and BRD4 BD1 and BD2 proteins with Ki of 2-20 nM.
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同义词QCA 276;QCA-276
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通路Chromatin/Epigenetic
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靶点Bromodomain
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受体Bromodomain
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研究领域——
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适应症——
化学信息
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CAS Number2126819-40-5
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分子量401.49
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分子式C22H19N5OS
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1=NN=C2N1C3=C(COC2)C(=C(S3)C#CC4=CN(N=C4)C)CC5=CC=CC=C5
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化学全称3-Benzyl-9-methyl-2-((1-methyl-1H-pyrazol-4-yl)ethynyl)-4H,6Hthieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Qin C, et al. J Med Chem. 2018 Jul 18. doi: 10.1021/acs.jmedchem.8b00506.
产品手册