Peretinoin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

A novel orally available, synthetic retinoid with potential antineoplastic and chemopreventive activities.

A novel orally available, synthetic retinoid with potential antineoplastic and chemopreventive activities; inhibits DEN-induced rat hepatocarcinogenesis through suppression of TGF-alpha expression and cell proliferation; decreases the levels of cyclin D1, cyclin D2, cIAP2 and XIAP proteins, and inhibits growth of ATL cells both in vitro and in vivo; prevents the progression of NASH and the development of HCC through activating the autophagy pathway by increased Atg16L1 expression in mice model; also inhibits HCV replication and infectious virus release in vitro.Liver Cancer Phase 3 Clinical

NIK-333;NIK333;NIK 333

Microbiology/Virology

HCV

HCV

Cancer

Liver Cancer

81485-25-8

302.45

C20H30O2

>98% (HPLC)

DMSO: ≥ 100 mg/mL; In vivo: Peretinoin is dissolved in DMSO (3 mg/mL) and then diluted with water (DMSO: water=1:1).

C/C(C)=C/CC/C(C)=C/CC/C(C)=C/C=C/C(C)=C/C(O)=O

2,4,6,10,14-Hexadecapentaenoic acid, 3,7,11,15-tetramethyl-, (2E,4E,6E,10E)-

(-20℃)

With Ice Pack

≥ 2 years