ABT-072 ( ABT072 )

产品货号. M10465 CAS No. 1132936-00-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

ABT-072
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ABT-072 is a novel, orally bioavailable non-nucleoside HCV NS5B polymerase inhibitor with EC50 of 0.3 nM (GT1b).
产品描述

ABT-072 is a novel, orally bioavailable non-nucleoside HCV NS5B polymerase inhibitor with EC50 of 0.3 nM (GT1b); a new direct-acting antivirals (DAAs) for the treatment of HCV infection.HCV Infection Phase 2 Discontinued
同义词

ABT072
通路

Microbiology/Virology
靶点

HCV
受体

HCV
研究领域

Infection
适应症

HCV Infection

CAS Number

1132936-00-5
分子量

469.56
分子式

C24H27N3O5S
纯度

>98% (HPLC)
溶解度

——
SMILES

CS(=O)(NC1=CC=C(/C=C/C2=CC(N(C(N3)=O)C=CC3=O)=CC(C(C)(C)C)=C2OC)C=C1)=O
化学全称

(E)-N-(4-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide

1. Randolph JT, et al. J Med Chem. 2018 Feb 8;61(3):1153-1163.

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