Paprotrain ( (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile )

产品货号. M26357 CAS No. 57046-73-8

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Paprotrain
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Paprotrain inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
产品描述

Paprotrain inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.(In Vitro):Paprotrain-treated porcine oocytes suffer failure of nuclear maturation.?The number of oocytes arrested at early MI stage increase in a dose-dependent manner after KIF20A activity inhibition, while the percentage of oocytes that reach ATI and MII stages decrease after treatment.
同义词

(alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile
通路

Cytoskeleton/Cell Adhesion Molecules
靶点

Kinesin
受体

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研究领域

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适应症

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1.Kennedy GL Jr, Chen HC, Hall GT. Inhalation toxicity of dehydrothio-p-toluidine. Food Chem Toxicol. 1984 Apr;22(4):289-92.

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Paprotrain inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
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