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MF-438

CAS No. 921605-87-0

MF-438 ( —— )

产品货号. M22502 CAS No. 921605-87-0

MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥1191 有现货
5MG ¥1831 有现货
10MG ¥2795 有现货
25MG ¥4747 有现货
50MG ¥6788 有现货
100MG ¥9396 有现货
500MG ¥18792 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    MF-438
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.
  • 产品描述
    MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.
  • 同义词
    ——
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Dehydrogenase
  • 受体
    SCD
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    921605-87-0
  • 分子量
    421.44
  • 分子式
    C19H18F3N5OS
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:62.5 mg/mL (148.30 mM; Need ultrasonic)
  • SMILES
    Cc1nnc(s1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1C(F)(F)F
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.
产品手册
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