MF-438
CAS No. 921605-87-0
MF-438 ( —— )
产品货号. M22502 CAS No. 921605-87-0
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥1191 | 有现货 |
|
5MG | ¥1831 | 有现货 |
|
10MG | ¥2795 | 有现货 |
|
25MG | ¥4747 | 有现货 |
|
50MG | ¥6788 | 有现货 |
|
100MG | ¥9396 | 有现货 |
|
500MG | ¥18792 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称MF-438
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.
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产品描述MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.
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同义词——
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体SCD
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研究领域——
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适应症——
化学信息
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CAS Number921605-87-0
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分子量421.44
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分子式C19H18F3N5OS
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纯度>98% (HPLC)
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溶解度DMSO:62.5 mg/mL (148.30 mM; Need ultrasonic)
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SMILESCc1nnc(s1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1C(F)(F)F
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.
产品手册
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