AGI-6780 ( AGI6780; AGI 6780; AGI-6780 )

产品货号. M11841 CAS No. 1432660-47-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

AGI-6780
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.
产品描述

AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.
同义词

AGI6780; AGI 6780; AGI-6780
通路

Metabolic Enzyme/Protease
靶点

Dehydrogenase
受体

IDH2 R140Q mutant
研究领域

Cancer
适应症

——

CAS Number

1432660-47-3
分子量

481.51
分子式

C21H18F3N3O3S2
纯度

>98%(HPLC)
溶解度

Ethanol: 96 mg/mL (199.37 mM); DMSO: 96 mg/mL (199.37 mM)
SMILES

O=S(C1=CC=C(C2=CSC=C2)C(NC(NC3=CC=CC(C(F)(F)F)=C3)=O)=C1)(NC4CC4)=O
化学全称

N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide

1.Wang F, et al. Science. 2013 May 3;340(6132):622-6.

计算器

产品手册

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