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MC-1568

CAS No. 852475-26-4

MC-1568 ( MC1568 )

产品货号. M16194 CAS No. 852475-26-4

A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥259 有现货
10MG ¥421 有现货
25MG ¥761 有现货
50MG ¥1175 有现货
100MG ¥2122 有现货
200MG ¥3686 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    MC-1568
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
  • 产品描述
    A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A; displays 176-fold selectivity over HD1-B; increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20 uM; promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.
  • 同义词
    MC1568
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    HD1-A(Maize);HD1-B(Maize)
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    852475-26-4
  • 分子量
    314.31
  • 分子式
    C17H15FN2O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 18.5 mg/mL
  • SMILES
    O=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C
  • 化学全称
    2-Propenamide, 3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-, (2E)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Mai A, et al. J Med Chem. 2005 May 5;48(9):3344-53.
2. Duong V, et al. Mol Cancer Res. 2008 Dec;6(12):1908-19.
3. Collins LM, et al. Mol Neurobiol. 2015;51(3):1432-42.
产品手册
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