MC-1568
CAS No. 852475-26-4
MC-1568 ( MC1568 )
产品货号. M16194 CAS No. 852475-26-4
A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥259 | 有现货 |
|
10MG | ¥421 | 有现货 |
|
25MG | ¥761 | 有现货 |
|
50MG | ¥1175 | 有现货 |
|
100MG | ¥2122 | 有现货 |
|
200MG | ¥3686 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称MC-1568
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
-
产品描述A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A; displays 176-fold selectivity over HD1-B; increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20 uM; promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.
-
同义词MC1568
-
通路Cell Cycle/DNA Damage
-
靶点HDAC
-
受体HD1-A(Maize);HD1-B(Maize)
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number852475-26-4
-
分子量314.31
-
分子式C17H15FN2O3
-
纯度>98% (HPLC)
-
溶解度DMSO: 18.5 mg/mL
-
SMILESO=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C
-
化学全称2-Propenamide, 3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-, (2E)-
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Mai A, et al. J Med Chem. 2005 May 5;48(9):3344-53.
2. Duong V, et al. Mol Cancer Res. 2008 Dec;6(12):1908-19.
3. Collins LM, et al. Mol Neurobiol. 2015;51(3):1432-42.
2. Duong V, et al. Mol Cancer Res. 2008 Dec;6(12):1908-19.
3. Collins LM, et al. Mol Neurobiol. 2015;51(3):1432-42.
产品手册
关联产品
-
Marbostat-100
Marbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM.
-
CM-675
CM-675 (CM675) is a potent, dual PDE5 and classI-HDAC inhibitor with IC50 of 114/673 nM for PDE5A/HDAC1, respectively.
-
CI-994
A potent, selective class I HDAC inhibitor with IC50 of 0.9/0.9/1.2 uM for HDAC1/2/3, respectively.