IDX-17119 ( IDX17119 )

产品货号. M13106 CAS No. 1987906-92-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

IDX-17119
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assay.
产品描述

IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assay; shows activity against broad genotype profile: IC50= 0.0099 uM, 0.2538 uM, 0.1809 uM and 0.0257 uM on genotypes 1b, 2a, 3a and 4a, respectively.
同义词

IDX17119
通路

Microbiology/Virology
靶点

HCV
受体

HCV
研究领域

——
适应症

——

CAS Number

1987906-92-2
分子量

531.51
分子式

C26H26N7O4P
纯度

>98% (HPLC)
溶解度

——
SMILES

CC1=CC(=C(C=C1)P(=O)(NC2=NN(C=C2C(=O)O)C3=CC=C(C=C3)C4=NN5C(=CC(=NC5=C4)C)N)OC)C
化学全称

1-(4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl)-3-(((2,4-dimethylphenyl)(methoxy)phosphoryl)amino)-1H-pyrazole-4-carboxylic acid

1. Pierra Rouvière C, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4536-41.

计算器

产品手册

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IDX-17119

IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assay.