• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

AL-9

CAS No. 869218-90-6

AL-9 ( HCV inhibitor AL-9 )

产品货号. M16312 CAS No. 869218-90-6

AL-9 is a small molecule HCV replication inhibitor with EC50 of 0.29 and 0.75 uM for genotype 1b and 2a.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    AL-9
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    AL-9 is a small molecule HCV replication inhibitor with EC50 of 0.29 and 0.75 uM for genotype 1b and 2a.
  • 产品描述
    AL-9 is a small molecule HCV replication inhibitor with EC50 of 0.29 and 0.75 uM for genotype 1b and 2a, inhibits purified PI4KIIIα with IC50 of 0.57 uM; inhibits HCV across different genotypes with activity in the sub-micromolar to low micromolar range in the absence of significant cytotoxic effects; inhibits PI4KIIIα also in living cells, while not appreciably affecting the activity of PI4KIIIβ, does not affect the level of PI4P in the Golgi membrane.
  • 同义词
    HCV inhibitor AL-9
  • 通路
    Microbiology/Virology
  • 靶点
    HCV
  • 受体
    HCV
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    869218-90-6
  • 分子量
    402.45
  • 分子式
    C23H22N4O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    OCC1=CC=C(C2=CC3=C(NC4=CC=C(N5CCOCC5)C=C4)N=CN=C3C=C2)O1
  • 化学全称
    (5-(4-((4-morpholinophenyl)amino)quinazolin-6-yl)furan-2-yl)methanol

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Bianco A, et al. PLoS Pathog. 2012;8(3):e1002576.
2. MacLeod AM, et al. ACS Med Chem Lett. 2013 May 8;4(7):585-9.
产品手册
关联产品
  • Filibuvir

    Filibuvir (PF-00868554;PF-868554) is a nonnucleoside, potent and selective, orally available HCV NS5B inhibitor with IC50 of 19 nM, EC50 of 75 nM.

  • Glecaprevir

    Glecaprevir (ABT 493;A 1282576) is a novel HCV NS3/4A protease inhibitor with pan-genotypic activity, inhibits NS3/4A proteases from HCV genotypes 1-6 in vitro with IC50 of 3.5-11.3 nM.

  • R-7128

    The prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase.