Voxilaprevir
CAS No. 1535212-07-7
Voxilaprevir ( GS-9857;GS9857 )
产品货号. M12165 CAS No. 1535212-07-7
Voxilaprevir (GS-9857)is a potent HCV NS3/4A protease inhibitor that is used in combination with sofosbuvir and velpatasvir for treatment of HCV infection.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥3216 | 有现货 |
|
10MG | ¥4771 | 有现货 |
|
25MG | ¥7655 | 有现货 |
|
50MG | ¥10368 | 有现货 |
|
100MG | ¥14013 | 有现货 |
|
500MG | ¥28026 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Voxilaprevir
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Voxilaprevir (GS-9857)is a potent HCV NS3/4A protease inhibitor that is used in combination with sofosbuvir and velpatasvir for treatment of HCV infection.
-
产品描述Voxilaprevir (GS-9857)is a potent HCV NS3/4A protease inhibitor that is used in combination with sofosbuvir and velpatasvir for treatment of HCV infection.HCV Infection Phase 2 Clinical
-
同义词GS-9857;GS9857
-
通路Microbiology/Virology
-
靶点HCV
-
受体HCV
-
研究领域Infection
-
适应症HCV Infection
化学信息
-
CAS Number1535212-07-7
-
分子量868.94
-
分子式C40H52F4N6O9S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCOC(C=C1)=CC2=C1N=C(C(O[C@@H](C3)[C@@H](CC)[C@@H](C(N[C@]4(C(NS(=O)(C5(C)CC5)=O)=O)C[C@H]4C(F)F)=O)N3C6=O)=N2)C(F)(F)CCCC[C@H]7[C@@H](C7)OC(N[C@H]6C(C)(C)C)=O
-
化学全称(33R,34S,35S,91R,92R,5S)-5-(tert-butyl)-N-((1R,2R)-2-(difluoromethyl)-1-(((1-methylcyclopropyl)sulfonyl)carbamoyl)cyclopropyl)-34-ethyl-14,14-difluoro-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Bourlière M, et al. N Engl J Med. 2017 Jun 1;376(22):2134-2146.
2. Gane EJ, et al. Gastroenterology. 2016 Nov;151(5):902-909.
3. Lawitz E, et al. Gastroenterology. 2016 Nov;151(5):893-901.e1.
2. Gane EJ, et al. Gastroenterology. 2016 Nov;151(5):902-909.
3. Lawitz E, et al. Gastroenterology. 2016 Nov;151(5):893-901.e1.
产品手册
关联产品
-
U18666A
U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.
-
Boceprevir
A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.
-
Telaprevir
A potent, selective, covalent, orally bioavailable inhibitor of HCV NS3/4A protease with Ki of 7 nM.