GDC-0927 ( GDC0927;SRN-927;RG-6047 )

产品货号. M12490 CAS No. 1642297-01-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

GDC-0927
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.
产品描述

GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.Breast Cancer Phase 1 Clinical
同义词

GDC0927;SRN-927;RG-6047
通路

Endocrinology/Hormones
靶点

Estrogen Receptor/ERR
受体

Estrogen Receptor/ERR
研究领域

Cancer
适应症

Breast Cancer

CAS Number

1642297-01-5
分子量

461.53
分子式

C28H28FNO4
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 100 mg/mL 216.68 mM
SMILES

CC1=C(C(OC2=C1C=C(C=C2)O)C3=CC=C(C=C3)OCCN4CC(C4)CF)C5=CC(=CC=C5)O
化学全称

(S)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6-ol

计算器

产品手册

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