GDC-0810 (ARN-810, Brilanestrant) is a non-steroidal, orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM (ER-α degradation).

Astragaloside IV is generally considered to be the primary active ingredient in Astragalus extract,an herbal extract which has been famous for literally thousands of years for its anti-aging properties.

Berberine is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism.