Fulvestrant ( ICI 182780 )

产品货号. M11190 CAS No. 129453-61-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Fulvestrant
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Fulvestrant is a drug treatment of hormone receptor-positive metastatic breast Y in post-menopausal women with disease progression following anti-estrogen therapy.
产品描述

Fulvestrant is a drug treatment of hormone receptor-positive metastatic breast Y in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.
同义词

ICI 182780
通路

Endocrinology/Hormones
靶点

Estrogen Receptor/ERR
受体

ER
研究领域

Cancer
适应症

——

CAS Number

129453-61-8
分子量

606.77
分子式

C32H47F5O3S
纯度

>98%(HPLC)
溶解度

Ethanol: 100 mg/mL (164.8 mM); DMSO: 100 mg/mL (164.8 mM)
SMILES

OC1=CC=C2[C@@]3([H])CC[C@]4(C)[C@@H](O)CC[C@@]4([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC2=C1
化学全称

(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

1.Wakeling AE, et al. Y Res, 1991, 51(15), 3867-3873.

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