• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Endoxifen

CAS No. 112093-28-4

Endoxifen ( —— )

产品货号. M10432 CAS No. 112093-28-4

A metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥656 有现货
5MG ¥1077 有现货
10MG ¥1725 有现货
25MG ¥3208 有现货
50MG ¥4998 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Endoxifen
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.
  • 产品描述
    A metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.Breast Cancer Phase 1 Clinical
  • 同义词
    ——
  • 通路
    Endocrinology/Hormones
  • 靶点
    Estrogen Receptor/ERR
  • 受体
    ER;ERR;hERGPotassiumChannel
  • 研究领域
    Cancer
  • 适应症
    Breast Cancer

化学信息

  • CAS Number
    112093-28-4
  • 分子量
    373.49
  • 分子式
    C25H27NO2
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCNC)C3=CC=CC=C3
  • 化学全称
    Phenol, 4-[(1Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Brauch H, et al. Clin Chem. 2009 Oct;55(10):1770-82.
2. Markopoulos C, et al. World J Clin Oncol. 2014 Aug 10;5(3):374-81.
3. Mugundu GM, et al. Drug Metab Dispos. 2012 Feb;40(2):389-96.
产品手册
关联产品
  • Ulipristal acetate

    Ulipristal acetate(CDB2914) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma.

  • α-Zearalenol

    α-Zearalenol is one of the major metabolites of Zearalenone. α-Zearalenol has structural analogy to estrogen, thus α-Zearalenol can bind to estrogen receptors (ERs).

  • Endoxifen (E-isomer)

    Endoxifen E-isomer is the E-isomer of (Z)-Endoxifen. Endoxifen E-isomer has antiestrogenic effects.