DMU-212

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

DMU-212, a methylated form of Resveratrol, shows antimitotic, antiproliferative, and antioxidant activities. DMU-212 induces mitotic arrest through the activation of ERK1/2 protein and the promotion of apoptosis.

DMU-212, a methylated form of Resveratrol, shows antimitotic, antiproliferative, and antioxidant activities. DMU-212 induces mitotic arrest through the activation of ERK1/2 protein and the promotion of apoptosis.(In Vitro):DMU-212 (0.3125-40 μM) inhibited the cellular proliferation of human melanoma cells at submicromolar or micromolar concentrations (IC50=0.5 μM, 0.5 μM, 1.25 μM, and 1.25 μM for A375, Bro, MeWo, and M5 human melanoma cells, respectively.).(In Vivo):In SCID female mice, DMU-212 (50 mg/kg; i.g.) inhibited tumor growth and lowered tumor burden.

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Apoptosis

Apoptosis

Tubulin polymerization

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134029-62-2

300.4

C18H20O4

>98% (HPLC)

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COC1=CC=C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)C=C1

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(-20℃)

With Ice Pack

≥ 2 years