LAT1-IN-1
CAS No. 20448-79-7
LAT1-IN-1 ( BCH )
产品货号. M23915 CAS No. 20448-79-7
LAT1-IN-1 (BCH) ?significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis.?
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥413 | 有现货 |
|
100MG | ¥737 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称LAT1-IN-1
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述LAT1-IN-1 (BCH) ?significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis.?
-
产品描述LAT1-IN-1 (BCH) ?significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis.?is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1).
-
同义词BCH
-
通路Apoptosis
-
靶点Apoptosis
-
受体LAT1;Apoptosis
-
研究领域——
-
适应症——
化学信息
-
CAS Number20448-79-7
-
分子量155.2
-
分子式C8H13NO2
-
纯度>98% (HPLC)
-
溶解度H2O:12.5 mg/mL (80.55 mM; Need ultrasonic);DMSO:< 1 mg/mL (insoluble or slightly soluble)
-
SMILESC1CC2CC1CC2(C(=O)O)N
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Ohshima Y, et al. Efficacy of system l amino acid transporter 1 inhibition as a therapeutic target in esophageal squamous cell carcinoma. Cancer Sci. 2016 Oct;107(10):1499-1505.
产品手册
关联产品
-
Sulforaphene
Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
-
NSC 146109 hydrochlo...
NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.
-
Methylisoindigotin
Meisoindigo(Natura-α; N-Methylisoindigotin; Dian III), a derivative of Indigo naturalis, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML).