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Elesclomol
CAS No. 488832-69-5
Elesclomol ( STA-4783;STA4783;STA 4783 )
产品货号. M14641 CAS No. 488832-69-5
Elesclomol (STA-4783) is a small-molecule oxidative stress inducer.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥275 | 有现货 |
|
| 10MG | ￥478 | 有现货 |
|
| 25MG | ￥761 | 有现货 |
|
| 50MG | ￥1037 | 有现货 |
|
| 100MG | ￥1320 | 有现货 |
|
| 200MG | ￥1968 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Elesclomol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Elesclomol (STA-4783) is a small-molecule oxidative stress inducer.
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产品描述Elesclomol (STA-4783) is a small-molecule oxidative stress inducer, exerts selective cytotoxicity by increasing intracellular concentrations of reactive oxygen species (ROS) and induces cell death via mitochondrial apoptosisin cancer cells; selectively kills cisplatin-resistant tumor cells through increased ROS, markedly enhances the therapeutic index of paclitaxel against human tumor xenograft models. Ovarian Cancer Phase 2 Clinical
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同义词STA-4783;STA4783;STA 4783
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通路Apoptosis
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靶点Apoptosis
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受体HSP70
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研究领域Cancer
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适应症Ovarian Cancer
化学信息
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CAS Number488832-69-5
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分子量400.52
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分子式C19H20N4O2S2
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 22 mg/mL
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SMILESO=C(NN(C)C(C1=CC=CC=C1)=S)CC(NN(C)C(C2=CC=CC=C2)=S)=O
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化学全称Propanedioic acid, 1,3-bis[2-methyl-2-(phenylthioxomethyl)hydrazide]
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Berkenblit A, et al. Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):584-90.
2. Kirshner JR, et al. Mol Cancer Ther. 2008 Aug;7(8):2319-27.
3. Wangpaichitr M, et al. Cancers (Basel). 2009;1(1):23-38.
4. Kluza J, et al. Cancer Res. 2012 Oct 1;72(19):5035-47.
2. Kirshner JR, et al. Mol Cancer Ther. 2008 Aug;7(8):2319-27.
3. Wangpaichitr M, et al. Cancers (Basel). 2009;1(1):23-38.
4. Kluza J, et al. Cancer Res. 2012 Oct 1;72(19):5035-47.
产品手册
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