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Boceprevir

CAS No. 394730-60-0

Boceprevir ( EBP 520;SCH 503034;EBP-520;EBP520;SCH-503034;SCH503034 )

产品货号. M14358 CAS No. 394730-60-0

A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥527 有现货
10MG ¥794 有现货
25MG ¥1239 有现货
50MG ¥1596 有现货
100MG ¥2576 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Boceprevir
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.
  • 产品描述
    A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays; displays >2000-fold selectivity over human neutrophil elastase (HNE).HCV Infection Approved
  • 同义词
    EBP 520;SCH 503034;EBP-520;EBP520;SCH-503034;SCH503034
  • 通路
    Microbiology/Virology
  • 靶点
    HCV
  • 受体
    HCVNS3protease
  • 研究领域
    Infection
  • 适应症
    HCV Infection

化学信息

  • CAS Number
    394730-60-0
  • 分子量
    519.68
  • 分子式
    C27H45N5O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 10 mg/mL
  • SMILES
    O=C([C@@H]1[C@@]2([H])C(C)(C)[C@@]2([H])CN1C([C@@H](NC(NC(C)(C)C)=O)C(C)(C)C)=O)NC(C(C(N)=O)=O)CC3CCC3
  • 化学全称
    3-Azabicyclo[3.1.0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-, (1R,2S,5S)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Venkatraman S, et al. J Med Chem. 2006 Oct 5;49(20):6074-86.
2. Sarrazin C, et al. Gastroenterology. 2007 Apr;132(4):1270-8.
3. Flint M, et al. Antimicrob Agents Chemother. 2009 Feb;53(2):401-11.
产品手册
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