Boceprevir
CAS No. 394730-60-0
Boceprevir ( EBP 520;SCH 503034;EBP-520;EBP520;SCH-503034;SCH503034 )
产品货号. M14358 CAS No. 394730-60-0
A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥527 | 有现货 |
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10MG | ¥794 | 有现货 |
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25MG | ¥1239 | 有现货 |
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50MG | ¥1596 | 有现货 |
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100MG | ¥2576 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Boceprevir
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays.
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产品描述A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays; displays >2000-fold selectivity over human neutrophil elastase (HNE).HCV Infection Approved
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同义词EBP 520;SCH 503034;EBP-520;EBP520;SCH-503034;SCH503034
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通路Microbiology/Virology
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靶点HCV
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受体HCVNS3protease
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研究领域Infection
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适应症HCV Infection
化学信息
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CAS Number394730-60-0
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分子量519.68
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分子式C27H45N5O5
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 10 mg/mL
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SMILESO=C([C@@H]1[C@@]2([H])C(C)(C)[C@@]2([H])CN1C([C@@H](NC(NC(C)(C)C)=O)C(C)(C)C)=O)NC(C(C(N)=O)=O)CC3CCC3
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化学全称3-Azabicyclo[3.1.0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-, (1R,2S,5S)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Venkatraman S, et al. J Med Chem. 2006 Oct 5;49(20):6074-86.
2. Sarrazin C, et al. Gastroenterology. 2007 Apr;132(4):1270-8.
3. Flint M, et al. Antimicrob Agents Chemother. 2009 Feb;53(2):401-11.
2. Sarrazin C, et al. Gastroenterology. 2007 Apr;132(4):1270-8.
3. Flint M, et al. Antimicrob Agents Chemother. 2009 Feb;53(2):401-11.
产品手册
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