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AG-636
CAS No. 1623416-31-8
AG-636 ( —— )
产品货号. M23718 CAS No. 1623416-31-8
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1345 | 有现货 |
|
| 10MG | ￥2211 | 有现货 |
|
| 25MG | ￥4496 | 有现货 |
|
| 50MG | ￥6464 | 有现货 |
|
| 100MG | ￥8829 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称AG-636
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
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产品描述AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
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同义词——
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体DHODH;DNA/RNA Synthesis
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研究领域——
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适应症——
化学信息
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CAS Number1623416-31-8
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分子量343.4
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分子式C21H17N3O2
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纯度>98% (HPLC)
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溶解度DMSO:31.25 mg/mL (91.01 mM; Need ultrasonic)
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SMILESO=C(C1=C(N(C)N=N2)C2=CC(C3=CC=C(C4=CC=CC=C4C)C=C3)=C1)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Gabrielle McDonald, et al. Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase. Mol Cancer Ther. 2020 Dec;19(12):2502-2515.
产品手册
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