• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

DHODH-IN-16

CAS No. 2511248-11-4

DHODH-IN-16 ( —— )

产品货号. M28280 CAS No. 2511248-11-4

DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2333 有现货
10MG ¥3718 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    DHODH-IN-16
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
  • 产品描述
    DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).(In Vitro):DHODH-IN-16 inhibited the growth of MOLM-13 cells effectively (IC50 = 0.2 nM) .
  • 同义词
    ——
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Dehydrogenase
  • 受体
    TNF-α
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2511248-11-4
  • 分子量
    436.5
  • 分子式
    C24H25FN4O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CCN(C(CO)=NN1c(cc(C(C(C)C)=CN(c2c(C)cccc2)C2=O)c2c2)c2F)C1=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Deng X, et al. Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors. Front Chem. 2018 Apr 4;6:98.
产品手册
关联产品
  • Glycyrrhizin

    Actions Biologically active constituent in the sweet root of Glycyrrhiza species (licorice). Antiviral.

  • ASLAN003

    ASLAN003 is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.

  • Octanoic acid

    CPI-613, a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism.