ABBV-744 ( ABBV744 )

产品货号. M13413 CAS No. 2138861-99-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

ABBV-744
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ABBV-744 (ABBV744) is a potent, BDII-selective BET bromodomain inhibitor.
产品描述

ABBV-744 (ABBV744) is a potent, BDII-selective BET bromodomain inhibitor, ABBV-744 is a potent, selective inhibitor of the AR transcription activity; induces tumor growth inhibition in LNCaP and MDA-Pca-2b xenograft models.Prostate Cancer Phase 1 Clinical
同义词

ABBV744
通路

Chromatin/Epigenetic
靶点

Bromodomain
受体

BET bromodomain
研究领域

Cancer
适应症

Prostate Cancer

CAS Number

2138861-99-9
分子量

491.56
分子式

C28H30FN3O4
纯度

>98% (HPLC)
溶解度

DMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
SMILES

O=C(C(N1)=CC(C(C2=CC(C(C)(O)C)=CC=C2OC3=C(C)C=C(F)C=C3C)=CN4C)=C1C4=O)NCC
化学全称

1H-Pyrrolo[2,3-c]pyridine-2-carboxamide, N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-

计算器

产品手册

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