FL-411
CAS No. 2118944-88-8
FL-411 ( FL411 )
产品货号. M13371 CAS No. 2118944-88-8
FL-411 is a novel small-molecule inhibitor of BRD4.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥721 | 有现货 |
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10MG | ¥1191 | 有现货 |
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25MG | ¥2406 | 有现货 |
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50MG | ¥4026 | 有现货 |
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100MG | ¥6707 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称FL-411
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述FL-411 is a novel small-molecule inhibitor of BRD4.
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产品描述FL-411 is a novel small-molecule inhibitor of BRD4, induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction and activating AMPK-mTOR-ULK1-modulated autophagic pathway in breast cancer cells; induces ACD pathways involved in HMGB1, VDAC1/2, and eEF2, displays a therapeutic potential on both breast cancer xenograft mouse and zebrafish models.
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同义词FL411
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通路Chromatin/Epigenetic
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靶点Bromodomain
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受体BRD4
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研究领域Cancer
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适应症——
化学信息
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CAS Number2118944-88-8
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分子量341.43
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分子式C18H19N3O2S
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纯度>98% (HPLC)
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溶解度( < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESCC1=CC(=CC(=C1O)C)C2=NC3=C(C4=C(S3)CN(CC4)C)C(=O)N2
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化学全称2-(4-Hydroxy-3,5-dimethylphenyl)-7-methyl-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Ouyang L, et al. J Med Chem. 2017 Dec 28;60(24):9990-10012.
产品手册
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