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YL0919
CAS No. 1339058-04-6
YL0919 ( YL-0919;YL 0919 )
产品货号. M11363 CAS No. 1339058-04-6
An orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥316 | 有现货 |
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| 5MG | ￥518 | 有现货 |
|
| 10MG | ￥648 | 有现货 |
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| 25MG | ￥988 | 有现货 |
|
| 50MG | ￥1604 | 有现货 |
|
| 100MG | ￥2989 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称YL0919
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述An orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively.
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产品描述An orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively; shows no affinity for dopamine receptors and others 5-HT receptors; inhibits forskolin-stimulated cAMP formation and 5-HT uptake in both rat cortical synaptosomes and recombinant cells; significantly reverses the depressive-like behaviors in chronically stressed rats.
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同义词YL-0919;YL 0919
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT; 5-HT1A
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number1339058-04-6
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分子量334.84
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分子式C18H23ClN2O2
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 30 mg/mL
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SMILESO=C1C=CC=CN1CC2(O)CCN(CC3=CC=CC=C3)CC2.[H]Cl
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化学全称2(1H)-Pyridinone, 1-[[4-hydroxy-1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Chen HX, et al. PLoS One. 2013 Dec 18;8(12):e83271.
2. Zhang LM, et al. Br J Pharmacol. 2017 May;174(9):769-780.
3. Qin JJ, et al. Neurosci Lett. 2014 Oct 17;582:104-8.
2. Zhang LM, et al. Br J Pharmacol. 2017 May;174(9):769-780.
3. Qin JJ, et al. Neurosci Lett. 2014 Oct 17;582:104-8.
产品手册
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