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SB-258585
CAS No. 209480-63-7
SB-258585 ( SB258585 )
产品货号. M13292 CAS No. 209480-63-7
SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥770 | 有现货 |
|
| 10MG | ￥1320 | 有现货 |
|
| 25MG | ￥2373 | 有现货 |
|
| 50MG | ￥4180 | 有现货 |
|
| 100MG | ￥5978 | 有现货 |
|
| 500MG | ￥12393 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SB-258585
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.
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产品描述SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes; also is an inhibitor of HCV entry in liver-derived cell lines as well as primary hepatocytes, modulates localization of the coreceptor tight junction protein claudin-1 (CLDN1) in a 5-HT6-independent manner, induces intracellular accumulation of CLDN1.
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同义词SB258585
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域——
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适应症——
化学信息
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CAS Number209480-63-7
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分子量487.36
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分子式C18H22IN3O3S
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纯度>98% (HPLC)
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溶解度——
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SMILESO=S(C1=CC=C(I)C=C1)(NC2=CC=C(OC)C(N3CCN(C)CC3)=C2)=O.[H]Cl
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化学全称4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Hirst WD, et al. Br J Pharmacol. 2000 Aug;130(7):1597-605.
2. Riva L, et al. J Virol. 2018 Apr 27;92(10). pii: e01982-17.
2. Riva L, et al. J Virol. 2018 Apr 27;92(10). pii: e01982-17.
产品手册
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