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Lofepramine

CAS No. 23047-25-8

Lofepramine ( Lopramine; Amplit; Leo 640; Gamanil )

产品货号. M26742 CAS No. 23047-25-8

Lofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥332 有现货
5MG ¥535 有现货
10MG ¥737 有现货
25MG ¥1523 有现货
50MG ¥2276 有现货
100MG ¥3418 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Lofepramine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Lofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine.
  • 产品描述
    Lofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors.
  • 同义词
    Lopramine; Amplit; Leo 640; Gamanil
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    Topo II
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    23047-25-8
  • 分子量
    419.0
  • 分子式
    C26H27ClN2O
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CN(CCCN1c2ccccc2CCc2ccccc12)CC(=O)c1ccc(Cl)cc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.J P Braybrooke, et al. A phase II study of Razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis. Clin Cancer Res.2000; 6(12):4697-704.
产品手册
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