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WAY-200070

CAS No. 440122-66-7

WAY-200070 ( WAY200070;WAY 200070 )

产品货号. M14497 CAS No. 440122-66-7

WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥405 有现货
5MG ¥648 有现货
10MG ¥915 有现货
25MG ¥1968 有现货
50MG ¥3483 有现货
100MG ¥5152 有现货
500MG ¥11016 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    WAY-200070
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM).
  • 产品描述
    WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM); induces galanin expression within gonadotropin hormone-releasing hormone-immunoreactive neurons in the female rat brain, causes and learn the socially acquired preferenc in mice, deonstrates the anxiolytic-like and antidepressant-like effects in vivo.
  • 同义词
    WAY200070;WAY 200070
  • 通路
    Endocrinology/Hormones
  • 靶点
    Estrogen Receptor/ERR
  • 受体
    ERRα;ERRβ
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    440122-66-7
  • 分子量
    306.11
  • 分子式
    C13H8BrNO3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 31 mg/mL
  • SMILES
    O=C1C=C/C(C=C1)=C2OC3=C(Br)C=C(O)C=C3N/2
  • 化学全称
    5-Benzoxazolol, 7-bromo-2-(4-hydroxyphenyl)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Hughes ZA, et al. Neuropharmacology. 2008 Jun;54(7):1136-42.
2. Clipperton AE, et al. Neuropsychopharmacology. 2008 Sep;33(10):2362-75.
3. Malamas MS, et al. J Med Chem. 2004 Oct 7;47(21):5021-40.
产品手册
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