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VPC-70063
CAS No. 13571-44-3
VPC-70063 ( Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)- )
产品货号. M28492 CAS No. 13571-44-3
VPC-70063 是 c-Myc-MAX 的抑制剂。 VPC-70063 对 Myc-Max 转录活性抑制为 106%，IC50 为 8.9 μM，对 Myc-Max/UBE2C 下游通路抑制为 94%。 VPC-70063可用于抗癌研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1742 | 有现货 |
|
| 10MG | ￥2406 | 有现货 |
|
| 25MG | ￥4479 | 有现货 |
|
| 50MG | ￥6391 | 有现货 |
|
| 100MG | ￥8748 | 有现货 |
|
| 500MG | ￥17658 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称VPC-70063
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述VPC-70063 是 c-Myc-MAX 的抑制剂。 VPC-70063 对 Myc-Max 转录活性抑制为 106%，IC50 为 8.9 μM，对 Myc-Max/UBE2C 下游通路抑制为 94%。 VPC-70063可用于抗癌研究。
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产品描述VPC-70063 is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C downstream pathway inhibition of 94%. VPC-70063 can be used for studies about anticancer.(In Vitro):VPC-70063 (6.25, 12.5, and 25 μM) causes apoptosis of LNCaP cells as indicated by cleavage of PARP. VPC-70063 (0-500 μM) disrupts the interaction of Myc-Max with DNA in a dose-dependent manner.
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体外实验VPC-70063 (25 μM; 96 h) shows Myc-Max transcriptional activity inhibition of 106% and Myc-Max/UBE2C downstream pathway inhibition of 94%.VPC-70063 (6.25-25 μM, 48 h) causes apoptosis of LNCaP cells as indicated by cleavage of PARP.VPC-70063 (0-500 μM; 0-600 s) disrupts the interaction of Myc-Max with DNA in a dose dependent manner.Western Blot Analysis Cell Line:LNCaP cells Concentration:6.25 μM, 12.5 μM and 25 μM Incubation Time:48 h Result:Induced PARP cleavage.
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体内实验——
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同义词Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-
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通路Apoptosis
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靶点Apoptosis
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受体P2X3
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研究领域——
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适应症——
化学信息
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CAS Number13571-44-3
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分子量378.33
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分子式C16H12F6N2S
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纯度>98% (HPLC)
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溶解度——
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SMILESFC(F)(F)C1=CC(=CC(=C1)C(F)(F)F)NC(=S)NCC=2C=CC=CC2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
