• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Uprifosbuvir

CAS No. 1496551-77-9

Uprifosbuvir ( MK3682;IDX 21437 )

产品货号. M12075 CAS No. 1496551-77-9

A novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥11907 有现货
50MG ¥24138 有现货
100MG ¥32400 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Uprifosbuvir
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.
  • 产品描述
    A novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.HCV Infection Phase 2 Clinical
  • 同义词
    MK3682;IDX 21437
  • 通路
    Microbiology/Virology
  • 靶点
    HCV
  • 受体
    HCV
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    1496551-77-9
  • 分子量
    545.91
  • 分子式
    C22H29ClN3O9P
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C[C@@H](C(OC(C)C)=O)N[P@@](OC1=CC=CC=C1)(OC[C@H]2O[C@@H](N(C(N3)=O)C=CC3=O)[C@](C)(Cl)[C@@H]2O)=O
  • 化学全称
    Propan-2-yl (2R)-2-{[(R)-({(2R,3R,4R,5R)-4-chloro-5-[2,4-dioxo-3,4dihydropyrimidin-1(2H)-yl]-3-hydroxy-4-methyloxolan-2yl}methoxy)(phenoxy)phosphoryl]amino}propanoate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Wyles D, et al. Hepatology. 2017 Jul 7. doi: 10.1002/hep.29358.
2. Lawitz E, et al. Lancet Gastroenterol Hepatol. 2017 Aug 9. pii: S2468-1253(17)30163-2.
产品手册
关联产品
  • MK-8325

    MK-8325 is a potent, selective pan-genotype HCV NS5A inhibitor with IC50 of 15, 1 and 3 pM for GT1a, GT1b and GT2a, respectively.

  • Myriocin

    Myriocin, a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids.

  • Voxilaprevir

    Voxilaprevir (GS-9857)is a potent HCV NS3/4A protease inhibitor that is used in combination with sofosbuvir and velpatasvir for treatment of HCV infection.