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Daclatasvir

CAS No. 1009119-64-5

Daclatasvir ( BMS-790052;EBP 883;BMS 790052 )

产品货号. M10059 CAS No. 1009119-64-5

A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥284 有现货
10MG ¥389 有现货
50MG ¥543 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Daclatasvir
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons.
  • 产品描述
    A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons; exhibits picomolar EC(50) towards replicons expressing a broad range of HCV genotypes and the JFH-1 genotype 2a infectious virus in cell culture.HCV Infection Approved
  • 同义词
    BMS-790052;EBP 883;BMS 790052
  • 通路
    Microbiology/Virology
  • 靶点
    HCV
  • 受体
    HCVNS5A
  • 研究领域
    Infection
  • 适应症
    HCV Infection

化学信息

  • CAS Number
    1009119-64-5
  • 分子量
    738.88
  • 分子式
    C40H50N8O6
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 40 mg/mL
  • SMILES
    COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C1=NC=C(N1)C1=CC=C(C=C1)C1=CC=C(C=C1)C1=CN=C(N1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r,c:19,25,27,32,34,39,t:17,23,30,37|
  • 化学全称
    Carbamic acid, N,N'-[[1,1'-biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Gao M, et al. Nature. 2010 May 6;465(7294):96-100.
2. Lemm JA, et al. Antimicrob Agents Chemother. 2011 Aug;55(8):3795-802.
3. Fridell RA, et al. Antimicrob Agents Chemother. 2010 Sep;54(9):3641-50.
4. Fridell RA, et al. J Virol. 2011 Jul;85(14):7312-20.
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