USP10-IN-3 ( —— )

产品货号. M16503 CAS No. 904448-58-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

USP10-IN-3
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
产品描述

USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3.
同义词

——
通路

Proteasome/Ubiquitin
靶点

DUB
受体

DUB
研究领域

——
适应症

——

CAS Number

904448-58-4
分子量

401.98
分子式

C23H32ClN3O
纯度

>98% (HPLC)
溶解度

——
SMILES

CCCN(CCC)CCCNC(=O)C1=CC2=C(C=C1)C(=C3CCCCC3=N2)Cl
化学全称

9-chloro-N-(3-(dipropylamino)propyl)-5,6,7,8-tetrahydroacridine-3-carboxamide

1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215.

计算器

产品手册

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