Trofinetide
CAS No. 853400-76-7
Trofinetide ( NNZ 2566 )
产品货号. M16197 CAS No. 853400-76-7
Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2454 | 有现货 |
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10MG | ¥3718 | 有现货 |
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25MG | ¥6116 | 有现货 |
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50MG | ¥8586 | 有现货 |
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100MG | ¥11583 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Trofinetide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
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产品描述Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration; improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury; significantly reduces injury-mediated up-regulation of IL-1beta, TNF-alpha, E-selectin and IL-6 mRNA in the injured brain in rats.Other Indication Phase 2 Clinical
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同义词NNZ 2566
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Other Indications
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适应症Other Disease
化学信息
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CAS Number853400-76-7
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分子量315.32
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分子式C13H21N3O6
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纯度>98% (HPLC)
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溶解度H2O : ≥ 50 mg/mL 158.57 mM
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SMILESO=C(O)CC[C@@H](C(O)=O)NC([C@@]1(C)N(C(CN)=O)CCC1)=O
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化学全称((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Bickerdike MJ, et al. J Neurol Sci. 2009 Mar 15;278(1-2):85-90.
2. Lu XC, et al. J Cereb Blood Flow Metab. 2009 Dec;29(12):1924-32.
3. Wei HH, et al. J Neuroinflammation. 2009 Aug 5;6:19.
2. Lu XC, et al. J Cereb Blood Flow Metab. 2009 Dec;29(12):1924-32.
3. Wei HH, et al. J Neuroinflammation. 2009 Aug 5;6:19.
产品手册
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