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Trofinetide

CAS No. 853400-76-7

Trofinetide ( NNZ 2566 )

产品货号. M16197 CAS No. 853400-76-7

Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2454 有现货
10MG ¥3718 有现货
25MG ¥6116 有现货
50MG ¥8586 有现货
100MG ¥11583 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Trofinetide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
  • 产品描述
    Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration; improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury; significantly reduces injury-mediated up-regulation of IL-1beta, TNF-alpha, E-selectin and IL-6 mRNA in the injured brain in rats.Other Indication Phase 2 Clinical
  • 同义词
    NNZ 2566
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Other Targets
  • 研究领域
    Other Indications
  • 适应症
    Other Disease

化学信息

  • CAS Number
    853400-76-7
  • 分子量
    315.32
  • 分子式
    C13H21N3O6
  • 纯度
    >98% (HPLC)
  • 溶解度
    H2O : ≥ 50 mg/mL 158.57 mM
  • SMILES
    O=C(O)CC[C@@H](C(O)=O)NC([C@@]1(C)N(C(CN)=O)CCC1)=O
  • 化学全称
    ((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Bickerdike MJ, et al. J Neurol Sci. 2009 Mar 15;278(1-2):85-90.
2. Lu XC, et al. J Cereb Blood Flow Metab. 2009 Dec;29(12):1924-32.
3. Wei HH, et al. J Neuroinflammation. 2009 Aug 5;6:19.
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