Silychristin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

水飞蓟汀是一种植物生长调节剂。 Silychristin 是一种抗肝毒性化合物。水飞蓟汀是辣根过氧化物酶和脂氧合酶的抑制剂。

Silychristin is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase.

Silychristin exhibits a strong inhibition of MCT8-mediated T3 uptake with an IC50 of 110 nM in MCT8 overexpressing MDCK1-cells.Silychristin causes no cytotoxic for fibroblasts.Silychristin (6.5-75 μM; 24 hours) diminishes UVA toxicity and reduces ROS generation, and the protective effect is dose-dependent.Silychristin (12.5μM, 25μM) reduces the metalloproteinase-1 (MMP-1) level in cells. Cell Viability Assay Cell Line:NHDF Concentration: 6.5 μM,12.5 μM,25 μM,50 μM,75 μM Incubation Time:24 hours Result:Diminished UVA toxicity and reduced ROS generation in dose-dependent.Cell Viability Assay Cell Line:NHDF Concentration:12.5 μM, 25 μM Incubation Time: Result:Reduced the metalloproteinase-1 (MMP-1) level in cells.

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Others

Other Targets

5-Lipoxygenase

Others-Field

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33889-69-9

482.44

C25H22O10

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (207.28 mM)

COc1cc(ccc1O)[C@@H]1Oc2c(cc(cc2O)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2O)[C@H]1CO

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(-20℃)

With Ice Pack

≥ 2 years