Tianeptinostat ( —— )

产品货号. M17049 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Tianeptinostat
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Tianeptinostat is a class I HDAC inhibitor with IC50 of 28, 33 and 51 nM for HDAC1, 2 and 3, respectively.
产品描述

Tianeptinostat is a class I HDAC inhibitor with IC50 of 28, 33 and 51 nM for HDAC1, 2 and 3, respectively, also inhibits HDAC6 (IC50=1.6 nM) but not HDAC5 (IC50>80 uM); has EC50 of 1.72+M4130 and 7.66 uM in H3K9ac and H4K12ac assays, respectively.
同义词

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通路

Cell Cycle/DNA Damage
靶点

HDAC
受体

HDAC
研究领域

——
适应症

——

CAS Number

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分子量

437.94
分子式

C20H24ClN3O4S
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

6-((3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)-N-hydroxyhexanamide

1. Zhao WN, et al. ACS Chem Neurosci. 2018 Jun 22. doi: 10.1021/acschemneuro.8b00116.

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