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Mocetinostat
CAS No. 726169-73-9
Mocetinostat ( MGCD0103;MGCD 0103;MGCD-0103 )
产品货号. M15781 CAS No. 726169-73-9
An isotype-selective small molecule HDAC inhibitor that selectively inhibits HDAC1 (IC50=0.15 uM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥292 | 有现货 |
|
| 10MG | ￥421 | 有现货 |
|
| 25MG | ￥648 | 有现货 |
|
| 50MG | ￥810 | 有现货 |
|
| 100MG | ￥1280 | 有现货 |
|
| 200MG | ￥1661 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Mocetinostat
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述An isotype-selective small molecule HDAC inhibitor that selectively inhibits HDAC1 (IC50=0.15 uM).
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产品描述An isotype-selective small molecule HDAC inhibitor that selectively inhibits HDAC1 (IC50=0.15 uM); also inhibits HDAC2/3/11; no effect on HDAC4/5/6/7/8; induces hyperacetylation of histones and caused cell cycle blockade in various human cancer cell lines; inhibits growth of human tumor xenografts in nude mice; orally bioactive.Blood Cancer Phase 2 Clinical
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同义词MGCD0103;MGCD 0103;MGCD-0103
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC1;HDAC11;HDAC2;HDAC3;HDAC4
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研究领域Cancer
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适应症Blood cancer
化学信息
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CAS Number726169-73-9
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分子量396.44
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分子式C23H20N6O
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESNC1=CC=CC=C1NC(=O)C1=CC=C(CNC2=NC=CC(=N2)C2=CN=CC=C2)C=C1
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化学全称Benzamide, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Fournel M, et al. Mol Cancer Ther. 2008 Apr;7(4):759-68.
2. Zhou N, et al. J Med Chem. 2008 Jul 24;51(14):4072-5.
3. Raeppel S, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):644-9.
2. Zhou N, et al. J Med Chem. 2008 Jul 24;51(14):4072-5.
3. Raeppel S, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):644-9.
产品手册
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