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Givinostat

CAS No. 732302-99-7

Givinostat ( ITF2357 )

产品货号. M15799 CAS No. 732302-99-7

Givinostat hydrochloride monohydrate is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.

纯度: >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥583 有现货
10MG ¥1037 有现货
25MG ¥2049 有现货
50MG ¥3750 有现货
100MG ¥5532 有现货
500MG ¥11745 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Givinostat
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Givinostat hydrochloride monohydrate is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
  • 产品描述
    Givinostat hydrochloride monohydrate is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
  • 同义词
    ITF2357
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    HD1-A; HD1-B; HD2
  • 研究领域
    Inflammation/Immunology
  • 适应症
    ——

化学信息

  • CAS Number
    732302-99-7
  • 分子量
    475.97
  • 分子式
    CHClNO
  • 纯度
    >98%(HPLC)
  • 溶解度
    DMSO:95 mg/mL (199.59 mM); Ethanol:3 mg/mL (6.3 mM); Water:<1 mg/mL (<1 mM)
  • SMILES
    O=C(OCC1=CC=C2C=C(CN(CC)CC)C=CC2=C1)NC3=CC=C(C(NO)=O)C=C3.[H]Cl.O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Li S, et al. Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. J Biol Chem. 2015 Jan 23;290(4):2368-78.
产品手册
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