Elevenostat
CAS No. 1454902-97-6
Elevenostat ( JB3-22 )
产品货号. M28876 CAS No. 1454902-97-6
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥316 | 有现货 |
|
10MG | ¥518 | 有现货 |
|
25MG | ¥988 | 有现货 |
|
50MG | ¥1596 | 有现货 |
|
100MG | ¥2973 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Elevenostat
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.
-
产品描述Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.(In Vitro):Elevenostat induced cell death in MM cell lines.(In Vivo):Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells.
-
同义词JB3-22
-
通路Cell Cycle/DNA Damage
-
靶点HDAC
-
受体Telomerase
-
研究领域——
-
适应症——
化学信息
-
CAS Number1454902-97-6
-
分子量315.3
-
分子式C16H17N3O4
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCOc(cccc1)c1NC(NCc(cc1)ccc1C(NO)=O)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Fleming AM, et al. Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry. 2018 Feb 13;57(6):991-1002.
产品手册
关联产品
-
ACY-1083
ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM). It is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms.
-
LMK-235
A selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively.
-
Pracinostat
Pracinostat (SB939) is a potent, orally active HDAC inhibitor that potently inhibits class I, II, and IV HDACsw with Ki of 15-100 nM, inhibits HDAC1 with IC50 of 77 nM.