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LMK-235
CAS No. 1418033-25-6
LMK-235 ( LMK 235;LMK 235 )
产品货号. M11747 CAS No. 1418033-25-6
A selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥373 | 有现货 |
|
| 10MG | ￥583 | 有现货 |
|
| 25MG | ￥1150 | 有现货 |
|
| 50MG | ￥2001 | 有现货 |
|
| 100MG | ￥3621 | 有现货 |
|
| 200MG | ￥5338 | 有现货 |
|
| 500MG | ￥7995 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称LMK-235
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively.
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产品描述A selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively; less potent for HDAC1/11/2/8; demonstrates activity against chemoresistant cancer cell lines in an MTT assay for cytotoxicity using human ovarian cancer cell lines A2780 and cisplatin resistant A2780CisR (IC50 =0.49 and 0.32 uM respectively).
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同义词LMK 235;LMK 235
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC4;HDAC5
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研究领域Cancer
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适应症——
化学信息
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CAS Number1418033-25-6
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分子量294.35
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分子式C15H22N2O4
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 30 mg/mL
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SMILESO=C(NOCCCCCC(NO)=O)C1=CC(C)=CC(C)=C1
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化学全称Benzamide, N-[[6-(hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Marek L, et al. J Med Chem. 2013 Jan 24;56(2):427-36.
2. Li A, et al. Eur J Pain. 2013 Sep;17(8):1156-67.
2. Li A, et al. Eur J Pain. 2013 Sep;17(8):1156-67.
产品手册
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