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Belinostat

CAS No. 414864-00-9

Belinostat ( PXD101 )

产品货号. M14420 CAS No. 414864-00-9

Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.

纯度: >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥316 有现货
10MG ¥502 有现货
25MG ¥794 有现货
50MG ¥1191 有现货
100MG ¥1758 有现货
200MG ¥2811 有现货
500MG ¥4682 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Belinostat
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
  • 产品描述
    Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
  • 同义词
    PXD101
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    HDAC
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    414864-00-9
  • 分子量
    318.35
  • 分子式
    C15H14N2O4S
  • 纯度
    >98%(HPLC)
  • 溶解度
    DMSO: 64 mg/mL (201.03 mM)
  • SMILES
    C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
  • 化学全称
    2-Propenamide, N-hydroxy-3-(3-((phenylamino)sulfonyl)phenyl)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Savickiene J, et al. anticancer Drugs. 2014 Sep;25(8):938-49.
产品手册
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