Belinostat
CAS No. 414864-00-9
Belinostat ( PXD101 )
产品货号. M14420 CAS No. 414864-00-9
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
纯度: >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥316 | 有现货 |
|
10MG | ¥502 | 有现货 |
|
25MG | ¥794 | 有现货 |
|
50MG | ¥1191 | 有现货 |
|
100MG | ¥1758 | 有现货 |
|
200MG | ¥2811 | 有现货 |
|
500MG | ¥4682 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Belinostat
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
-
产品描述Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
-
同义词PXD101
-
通路Cell Cycle/DNA Damage
-
靶点HDAC
-
受体HDAC
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number414864-00-9
-
分子量318.35
-
分子式C15H14N2O4S
-
纯度>98%(HPLC)
-
溶解度DMSO: 64 mg/mL (201.03 mM)
-
SMILESC1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
-
化学全称2-Propenamide, N-hydroxy-3-(3-((phenylamino)sulfonyl)phenyl)-
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册
关联产品
-
LB-205
A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.
-
OBP-801
OBP-801 (YM 753;Spiruchostatin A) is a novel cyclic-peptide-based HDAC inhibitor with IC50 of 2 nM.
-
Panobinostat
A potent, broad-spectrum HDAC inhibitor with IC50 of 5-20 nM in cell-free assyas.