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LB-205

CAS No. 1113025-86-7

LB-205 ( LB 205;LB205 )

产品货号. M10416 CAS No. 1113025-86-7

A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
50MG ¥16038 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    LB-205
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.
  • 产品描述
    A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo; significantly enhances the migration of astrocytes and accelerates wound repair more effectively than SAHA and VPA; up-regulates the expression of NGF, phospho-TrkA, p-AKT, NF-κB, and Bcl-2, while down-regulates the expression of p75 NTR, phospho-JNK, and Bax.
  • 同义词
    LB 205;LB205
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    HDAC
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1113025-86-7
  • 分子量
    343.45
  • 分子式
    C18H21N3O2S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(NCCCCCC(NC1=CC=CC=C1)=O)C2=CC=CC=C2S
  • 化学全称
    2-mercapto-N-(6-oxo-6-(pyridin-3-ylamino)hexyl)benzamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Lu J, et al. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21200-5.
2. Lu J, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10747-52.
产品手册
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