Chidamide ( CS055; CS-055; CS 055; HBI8000; HBI 8000; HBI-8000; Chidamide; Tucidinostat )

产品货号. M15838 CAS No. 743420-02-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Chidamide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Chidamide(CS055; HBI-8000) is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM).
产品描述

Chidamide(CS055; HBI-8000) is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM); no inhibition on HDAC4/5/7/9/6(IC50>30 uM).
同义词

CS055; CS-055; CS 055; HBI8000; HBI 8000; HBI-8000; Chidamide; Tucidinostat
通路

Cell Cycle/DNA Damage
靶点

HDAC
受体

HDAC1; HDAC2; HDAC3; HDAC8
研究领域

Cancer
适应症

——

CAS Number

743420-02-2
分子量

390.41
分子式

C22H19FN4O2
纯度

>98%(HPLC)
溶解度

DMSO: 10 mM
SMILES

O=C(NC1=CC(F)=CC=C1N)C2=CC=C(CNC(/C=C/C3=CC=CN=C3)=O)C=C2
化学全称

(E)-N-(2-amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide

1. L, et al. Biochem Biophys Res Commun. 2010 Feb 5;392(2):190-5.

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