UF-010 ( UF010;UF 010 )

产品货号. M14914 CAS No. 537672-41-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

UF-010
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A potent and selective inhibitor of class I HDACs.
产品描述

A potent and selective inhibitor of class I HDACs with IC50s of 0.5/0.1/0.06/1.5/9.1/15.3/44.5 uM for HDAC1/2/3/8/6/10/11 respectively; shows no effect on HDAC4/5/7/9(>100 uM); induces the accumulation of protein acetylation and inhibits proliferation of NCI-60 panel of cancer cell lines (mean GI50=2.94 uM); a competitive with a fast-on/slow-off HDAC-binding mechanism.
同义词

UF010;UF 010
通路

Cell Cycle/DNA Damage
靶点

HDAC
受体

HDAC
研究领域

Cancer
适应症

——

1. Wang Y, et al. Chem Biol. 2015 Feb 19;22(2):273-84.

计算器

产品手册

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