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UF-010

CAS No. 537672-41-6

UF-010 ( UF010;UF 010 )

产品货号. M14914 CAS No. 537672-41-6

A potent and selective inhibitor of class I HDACs.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥373 有现货
25MG ¥689 有现货
50MG ¥1199 有现货
100MG ¥2001 有现货
200MG ¥2600 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    UF-010
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent and selective inhibitor of class I HDACs.
  • 产品描述
    A potent and selective inhibitor of class I HDACs with IC50s of 0.5/0.1/0.06/1.5/9.1/15.3/44.5 uM for HDAC1/2/3/8/6/10/11 respectively; shows no effect on HDAC4/5/7/9(>100 uM); induces the accumulation of protein acetylation and inhibits proliferation of NCI-60 panel of cancer cell lines (mean GI50=2.94 uM); a competitive with a fast-on/slow-off HDAC-binding mechanism.
  • 同义词
    UF010;UF 010
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    HDAC
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    537672-41-6
  • 分子量
    271.15
  • 分子式
    C11H15BrN2O
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    O=C(NNCCCC)C1=CC=C(Br)C=C1
  • 化学全称
    Benzoic acid, 4-bromo-, 2-butylhydrazide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Wang Y, et al. Chem Biol. 2015 Feb 19;22(2):273-84.
产品手册
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